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donate sign up to our newsletter donate -- breast cancer uk pinterest twitter facebook linkedin youtube home resources privacy policy policy & campaigns prevention week 17 to 23 september 2018 make your voice heard - write to your mp a manifesto for the prevention of breast cancer eu policy on edcs brexit and public health uk public health policy bisphenol a and other bisphenols flame retardants trade and industry pesticides and biocides science & research background briefings our grants apply for a grant -- background briefings air pollution aluminium salts in antiperspirants biology of breast cancer bisphenol a cosmetics and personal hygiene products endocrine disrupting chemicals flame retardants glyphosate in-utero exposures male breast cancer parabens top five tips to reduce your risk our grants oestrogenicity of anti-ageing face creams effects of low-dose edc mixtures king's college london reading university leeds university (dr thorne) leeds university (dr matthews) university of east anglia apply for a grant reduce your risk 5 top tips to reduce your risk #ditchthejunk are you being exposed? protect your baby's health book a let's prevent breast cancer talk a-z of harmful chemicals useful links and resources fundraise sign up to one of our fundraising campaigns wear it orange pamper for prevention 50k my way virtual fitness fundraiser 2019 research projects put the "fun" into your fundraising challenge yourself do you shop online? give a car payroll giving - working for a good cause let them eat cake are you game? sporting event charity cards donation in memory create an in memory page leaving a legacy business partnerships corporate partnerships policy donations in kind donations from cause related marketing corporate giving payroll giving employee fundraising and events some of our business supporters memory wall fundraising resources and downloadables 50k my way sweepstake sending in your money volunteer breast cancer uk ambassador programme ambassador registration form book a 'let's prevent breast cancer' talk collection box volunteer about us what we do our trustees our team current opportunities your opinion counts - give us your feedback information standard news & blog media archive guest blogger guidelines donate -- no more bpa scientific evidence links our routine exposure to bpa to a range of diseases, including breast cancer. as diet continues to be our main route of exposure to bpa, breast cancer uk is calling for it to be removed from all food and drinks packaging and replaced with safer alternatives. what is bpa? bpa is a man-made chemical first synthesised in the 1890s (1). it was discovered to mimic the hormone oestrogen in the 1930s (2). during the 1950s the chemical industry discovered that bpa could be used to make hard plastics, known as polycarbonates, and started to use it widely in various products (3). how does bpa affect my body? bpa is an endocrine disrupting chemical (edc). it is able to mimic oestrogen and can bind to the oestrogen receptors in a cell (4). some studies have found that it can affect the development of mammary glands (e.g. reviewed in 5). bpa has been linked to breast cancer (e.g. 6), as well as to prostate cancer (e.g. 7), heart disease (e.g. 8), obesity (e.g. 9) and diabetes (e.g. 10). why ban it from food and drinks packaging? scientific studies have found that an important route of exposure to bpa is via our food and drink. bpa leaches from the packaging and into the products, especially when they are scratched or heated during cooking and in the dishwasher (e.g. reviewed in 11). bpa is still used in a lot of plastic food and drinks packaging - microwave ovenware, storage containers, water and milk bottles as well as plastic tableware and cutlery, which is especially popular for toddlers and young children. it is also used to make the epoxy resins that line tins of food, such as baked beans, soup and tomatoes and cans of fizzy and alcoholic drinks. the european food safety authority recently conducted an assessment on bpa toxicity and exposures (12). despite acknowedging that “uncertainties” remain around the potential health effects of bpa on the mammary gland, reproductive, metabolic, neurobehavioural and immune systems, efsa concluded that bpa poses "no risk" to human health - a conclusion we have significant concerns about . many scientists remain unconvinced about the safety of bpa. they warn that even a low daily dose can have adverse affects (e.g. 13). breast cancer uk submitted evidence to both of efsa's consultations expressing concern that studies relating to low dose exposures had been dismissed (see opposite). we will continue to call for a ban on the use of bpa in food and drinks packaging on the basis that studies show that low dose exposures to bpa have been shown to have an adverse effect on the mammary gland. read more about bpa references (1) vogel, s. (2009) the politics of plastics: the making and unmaking of bisphenol a “safety” am j public health. 2009 november; 99(3): s559–s566. doi: 10.2105/ajph.2008.159228 (2) dodds, e.c. and lawson w. synthetic oestrogenic agents without the phenanthrene nucleus. nature. 1936;137(3476):996 (3) vogel, s. (2009) op. cit. (4) hiroi, h., o. tsutsumi, et al. (1999). ‘differential interactions of bisphenol a and 17beta-estradiol with estrogen receptor alpha (eralpha) and erbeta.’ endocr 46(6): 773-778. (5) anses (2013) assessment of the health risks of bisphenol a (6) fernandez, s. v. et al. (2012). 'expression and dna methylation changes in human breast epithelial cells after bisphenol a (bpa) exposure.' int j oncol. 2012 july; 41(1): 369–377. published online 2012 april 20. doi:10.3892/ijo.2012.1444. (7) vom saal, f. s., cooke, p.s., buchanan, d.l., palanza, p., thayer, k.a., nagel, s.c., parmigiani, s., welshons, w.v. (1998). ‘a physiologically based approach to the study of bisphenol a and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behavior.’ toxicol ind health 14: 239-260. (8) melzer, d., n. j. osborne, et al. (2012). ‘urinary bisphenol a concentration and risk of future coronary artery disease in apparently healthy men and women.’ circulation 125(12): 1482-1490. and shankar, a., s. teppala, et al. (2012). ‘bisphenol a and peripheral arterial disease: results from the nhanes.’ environ health perspect (9) shankar, a., s. teppala, et al. (2012). ‘urinary bisphenol a levels and measures of obesity: results from the national health and nutrition examination survey 2003-2008.’ isrn endocrinol 2012: 965243. (10) shankar, a. teppala, s. (2011). ‘relationship between urinary bisphenol a levels and diabetes mellitus.’ j clin endocrinol metab 96(12): 3822-3826. (11) european food safety authority (efsa) (2012) 'food is main source of bpa for consumers, thermal paper also potentially significant' http://www.efsa.europa.eu/en/press/news/130725.htm (12) efsa (2015) no consumer health risk from bpa exposure: http://www.efsa.europa.eu/en/press/news/150121.htm (13) vandenberg, l. n., t. colborn, et al. (2012). ‘hormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responses.’ endocr rev 33(3): 378-455. breast cancer uk submission to efsa consultation (part 2) read our submission to efsa’s consultation on risks to public health related to bpa in foodstuffs (part 2: health risks) download pdf breast cancer uk submission to efsa consultation (part 1) read our submission to efsa’s consultation on human exposures to bpa (part 1: human exposures) download pdf read more about bisphenol a breast cancer uk information sheet on bpa download pdf body of evidence report an overview of the low dose effects of bisphenol a in relation to breast cancer. download pdf how can you help reduce your risk reduce the levels of bpa in your body related news news: bpa alternatives, are they safe? read full story breast cancer uk calls for ‘prevention first’ in new manifesto read full sto

URL analysis for nomorebpa.org.uk

https://www.breastcanceruk.org.uk/reduce-your-risk/protect-your-babys-health/
https://www.breastcanceruk.org.uk/volunteer/collection-box-volunteer/
https://www.breastcanceruk.org.uk/fundraise/make-a-donation/employee-fundraising-and-events/
https://www.breastcanceruk.org.uk/policy-campaigns/prevention-week-17-to-23-september-2018/
https://www.breastcanceruk.org.uk/fundraise/make-a-donation/corporate-giving/
https://www.breastcanceruk.org.uk/volunteer/breast-cancer-uk-ambassador-programme/
https://www.breastcanceruk.org.uk/fundraise/make-a-donation/leaving-a-legacy/
https://www.breastcanceruk.org.uk/reduce-your-risk/useful-links-and-resources
https://www.breastcanceruk.org.uk/science-and-research/background-briefings/bisphenol-a
https://www.breastcanceruk.org.uk/fundraise/make-a-donation/some-of-our-business-supporters/
https://www.breastcanceruk.org.uk/reduce-your-risk/are-you-being-exposed/
https://www.breastcanceruk.org.uk/science-and-research/our-grants/
https://www.breastcanceruk.org.uk/fundraise/make-a-donation/payroll-giving/
https://www.breastcanceruk.org.uk/reduce-your-risk/useful-links-and-resources/
https://www.breastcanceruk.org.uk/uploads/bcuk_fact_sheet_bisphenol_a_%28print%29.pdf

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